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Sobelin (Cleocin)
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Sobelin

Sobelin is used for treating serious infections caused by certain bacteria. Sobelin is a lincomycin antibiotic. Sobelin kills sensitive bacteria by stopping the production of essential proteins needed by the bacteria to survive.

Other names for this medication:
Antirobe, Basocin, Biodaclin, Chloramphenicol, Clendix, Cleocin, Clidan, Climadan, Clinacin, Clinda, Clindacin, Clindacne, Clindagel, Clindahexal, Clindal, Clindamax, Clindamicina, Clindasol, Clindesse, Clindets, Clinium, Clinsol, Clinwas, Cutaclin, Dalacin, Dentomycin, Derma, Dermabel, Evoclin, Klimicin, Klindamicin, Klindan, Mediklin, Tidact, Ziana, Zindaclin

Similar Products:
Clinda derm, Clindagel, Clindets

 

Also known as:  Cleocin.

Description

Sobelin is a prescription medication used to treat bacterial infections of the lungs, skin, blood, bones, joints, female reproductive system, and internal organs.

Sobelin belongs to a group of drugs called lincomycin antibiotics. These work by stopping the growth of bacteria.

This medication is available as a vaginal cream, vaginal suppository, oral capsule, and oral liquid.

This medication is also available in injectable forms to be given directly into a vein (IV) or a muscle (IM) by a healthcare professional.

Common side effects of Sobelin include nausea, vomiting, joint pain, heartburn, pain when swallowing, and white patches in the mouth.

Dosage

Take Sobelin exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Take the capsule with a full glass of water to keep it from irritating your throat.

Measure the oral liquid with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Sobelin is sometimes given as an injection into a muscle, or injected into a vein through an IV. You may be shown how to use injections at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

Use a disposable needle only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.

To make sure this medicine is not causing harmful effects, you may need frequent medical tests during treatment.

If you need surgery, tell the surgeon ahead of time that you are using Sobelin.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Sobelin will not treat a viral infection such as the flu or a common cold.

Store at room temperature away from moisture and heat. Protect the injectable medicine from high heat.

Do not store the oral liquid in the refrigerator. Throw away any unused oral liquid after 2 weeks.

Overdose

In the event the patient misses a dose of Sobelin, the patient should take it as soon as possible. However, if it is almost time for the next scheduled dose, taking another dose of Sobelin may cause an overdose which can lead to serious health complications. In this case, the missed dose should be skipped entirely to avoid an overdose potential. If an overdose of Sobelin is suspected the patient should seek immediate medical intervention and assessment. An overdose may involve symptoms such as changes in mood or behaviors, thoughts of self harm, suicidal thoughts, seizures, or convulsions.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Sobelin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Generic Sobelin if you are allergic to Generic Sobelin components or to to tartrazine.

Be very careful if you're pregnant or you plan to have a baby, or you are a nursing mother.

Try to be very careful with Generic Sobelin if it is given to children younger than 10 years old who have diarrhea or an infection of the stomach or bowel. Elderly patient should use Generic Sobelin with caution.

Be sure to use Generic Sobelin for the full course of treatment.

Avoid alcohol.

It can be dangerous to stop Generic Sobelin taking suddenly.

sobelin flunarizine 5 mg

The in-vitro activity of four peptide antibiotics against 43 penicillin-resistant Streptococcus pneumoniae isolated from cerebrospinal fluid (CSF) was evaluated. The activity of SKF104662 was slightly greater to that of vancomycin, teicoplanin and daptomycin (MICs for 90% of the isolates tested 0.06, 0.25, 0.12 and 0.25 mg/L, respectively) and superior to the other 15 drugs tested. The serotype of these penicillin-resistant strains was also determined. The strains that belonged to the predominant serotype 9 were resistant only to penicillin. All six erythromycin- and clindamycin-resistant strains belonged to serotype 6 and three of them were also resistant to chloramphenicol and tetracycline (plus penicillin).

sobelin 300 mg

The effectiveness of traditional endodontic intracanal medications in reducing bacterial numbers and preventing acute flare-ups and pain continues to be questioned. In the present study, a new local delivery device was developed that releases a substantive dose of clindamycin into root canals. Clindamycin-impregnated ethylene vinyl acetate (EVA) fibers were produced, and the sensitivity of common endodontic microbes to the fibers were established. An in vitro model was developed to persistently infect 32 extracted human teeth with endodontic pathogens to test the efficacy of the clindamycin/EVA fibers in reducing the number of colony-forming units. The clindamycin/EVA fibers were shown to be effective in reducing growth of common endodontic microbes on blood agar plates, and in significantly reducing growth of Prevotella intermedia, Fusobacterium nucleatum, and Streptococcus intermedius in extracted human teeth, thus indicating merit in further exploring the potential of these fibers as intracanal medications.

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The pig-related MRSA collection, built up between January 1st 2003 and November 30th 2006 in the Regional Laboratory for Medical Microbiology and Infection Prevention (RLMMI) of the Jeroen Bosch Hospital, Den Bosch, The Netherlands, was tested for sensitivity to a large number ofantibiotics.

sobelin antibiotic

目的:分析并发下呼吸道感染尘肺病患者痰培养标本病原菌分布及耐药性,以指导临床合理使用抗菌药物。 方法:对2008年1月至2012年12月收集到的214例尘肺病患者的2 199份合格痰标本进行常规细菌及真菌培养,用梅里埃API分离菌株及东方旗云应用软件进行细菌鉴定,用NCCLS推荐的K-B法进行药物敏感试验。 结果:痰标本中共分离出病原菌508株,阳性率为23.1%,以真菌、革兰阴性杆菌为主,检出率分别为50.0%、40.7%。细菌鉴定结果显示,痰标本中最常见病原菌依次为白假丝酵母、铜绿假单胞菌、鲍曼不动杆菌。药敏结果显示,铜绿假单胞菌对头孢曲松(非脑膜炎)敏感率为100%,鲍曼不动杆菌对氨苄西林/舒巴坦、头孢哌酮/舒巴坦、亚胺培南敏感率为100%,此两种菌对其余常用的多种抗菌药物均有不同程度的耐药,尤其对头孢噻吩、克林霉素等多种常用药物敏感率为0。 结论:并发下呼吸道感染尘肺病患者以真菌和铜绿假单胞菌、鲍曼不动杆菌引起的感染为主,耐药现象严重。应依据病原菌检测及药敏试验结果,结合临床症状合理选用抗生素。.

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Some of my patients have been diagnosed with bacterial vaginousis (BV) during pregnancy; some have symptoms, others do not. Should I be treating them, and if so, with what? Also, should I be screening all my pregnant patients for BV?

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The current high (38%) prevalence of erythromycin-resistant S. pyogenes in Central and Southern Greece requires continuous surveillance and careful antibiotic policy.

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The aim of this study was to determine the serotype profile and antibiotyping of Streptococcus pneumoniae from nasal isolates in children. Nasopharyngeal swab samples obtained from 125 children were cultivated and screened for the presence of S. pneumoniae. Strains were identified according to standard microbiological methods. The isolates were serotyped by the Quellung reaction and resistance patterns were determined by the microdilution method according to NCCLS guidelines. Results indicate an overall pneumococcal carriage rate of 24% (n = 30). The most commonly isolated serotypes were 23F (20%), 6B (20%) and 14 (13%). 73% of isolates were resistant at least to one of the tested antibiotics. 47% of the strains were consistently resistant to penicillin and the serotypes 6B and 23F were frequently associated with this marker. 60% of the strains were resistant to doxycycline, 37% to trimethoprim/sulfamethoxazole and clindamycin, 30% to erythromycin, 23% to cloramphenicol, 7% to ceftriaxone and 3% to cefepime. All strains were sensible to ofloxacin, rifampin and vancomycin. The most common combined resistance patterns were PNC-ERI-TMP/SMX-DOX-CLO-CLI (16.59%) and PNC-DOX (13.27%). The results obtained in this study will allow to orient the empiric therapy for pneumococcal infections and a rational use of antibiotics in clinical practice, as well as the application of an appropriate vaccination program specially adapted to the serotypes more frequently found in children.

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A prospective, randomized, single-blind study evaluated the efficacy and safety of clindamycin plus amikacin versus clindamycin plus aztreonam (Cl-Az) in treating intraabdominal infections in adults.

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MRSA was isolated in 110 patients (30% of patients with S. aureus-positive cultures). PFGE detected three major clones (in 93% of patients), all of which had been present in 1999-2000, although in different proportions. Whereas the predominant clone in 1999 was clone A (clone A 63%, clone B 20%), clone B was now found to predominate (clone B 58%, clone A 19%). None of these major clones were related to the five pandemic clones, including the Iberian clone, but two of them seemed to be related to the two most prevalent clones in Spain at this time. The new predominant clone was more resistant than the others, and showed uniform resistance to ciprofloxacin, erythromycin, clindamycin, and gentamicin.

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Infants were managed with broad spectrum antibiotics including Clindamycin. Needle aspiration was attempted in one case.

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sobelin antibiotic 2015-03-14

Community-acquired acute lung abscess is usually caused by multiple anaerobic and less frequently aerobic Gram-positive microorganisms, which should respond to empirical therapy with amoxicillin-clavulanate, chloramphenicol, or a combination of penicillin and metronidazole. Tuberculosis, which may be indistinguishable from an acute lung abscess, occurred in 21% of patients Amoxidal Suspension in our study. Most bacterial pathogens are sensitive to conventional antimicrobial therapy and further investigation with percutaneous lung aspiration or bronchoscopy is indicated only when there is lack of early response to therapy or there is the presence of atypical clinical features.

sobelin 150 mg n1 2015-11-25

A real-world intervention to reduce primary care prescribing of Ciproxin 500 Mg Dose antimicrobials associated with CDI led to large, sustained reductions in the targeted prescribing, largely due to substitution with guideline-recommended antimicrobials rather than by avoiding antimicrobial use altogether. Further research is needed to examine the impact on antimicrobial resistance.

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To offer guidelines for the use of Zinacef Dosing Chart cefotetan, a cephamycin antibiotic, in order to minimize its overprescription.

sobelin 300 mg dosierung 2017-08-04

All antimicrobial drugs may produce toxic and allergic reactions. Penicillins and cephalosporins cause the greatest number of allergic reactions and should not be used for treatment of minor infections in patients with a history of an adverse reaction. If no alternative antibiotic will suffice Azithromycin 250 Mg Espanol for treatment of a serious infection, skin testing is necessary. Two commonly used antimicrobials, clindamycin and isoniazid, can have potentially fatal toxic effects.

sobelin 40 mg 2016-04-04

Langerhans cell histiocytosis (LCH) is a rare disease of unknown origin with a heterogeneous clinical presentation, varying from benign and self-limited to lethal. It is classified as single or multisystemic, according to the number of organs involved (one or at least two, respectively). Diagnosis can be challenging and is based on the histological and immunophenotypic examination of affected tissues. Secondary haemophagocytic lymphohistiocytosis is rarely reported in association with LCH and may impair its diagnosis. Some authors suggest that the coexistence of the two disorders is more than coincidental. We present a case of multisystem LCH in a 5-month-old Suprax 100 Dosage infant, with all risk organs involved, in which severity and rapid progression reflect an association with haemophagocytic syndrome.

sobelin 600 mg 2015-01-25

Although systemic Levaquin Class Of Drug anthrax infection is rare, it should be considered when faced with severe cutaneous infection in IVDU patients. This case shows that patients with significant bacteraemia may present with no signs of haemodynamic compromise. Prompt recognition and treatment with high dose IV antimicrobial therapy increases the likelihood of survival. The use of simple wound therapy adjuncts such as NPWT can give excellent wound healing results.

sobelin 300 mg alkohol 2016-12-06

Isolates of Mycoplasma hominis collected from patients in Boston and New York between 1976 and 1989 were studied. Minimal metabolism-inhibiting concentrations (MMCs) were determined by use of a terminal color change-broth dilution method, as well as by an agar inoculum-broth dilution method. Both methods gave comparable results. Tetracycline MMCs for 3 (7.0%) of 43 isolates of M. hominis collected from 1976 to 1979 were 8 micrograms/ml or more, but they were 8 micrograms/ml or more for 11 (20.3%) of 54 isolates collected from 1980 to 1983 (P = 0.083) and 16 (26.6%) of 60 isolates collected from 1984 to 1989 (P = 0.019). Similarly, doxycycline MMCs for 0 of 43 isolates of M. hominis collected from 1976 to 1979 were 8 micrograms/ml or more, but they were 8 micrograms/ml or more for 8 (14.8%) of 54 strains isolated from 1980 to 1983 (P = 0.0082) and 10 (16.6%) of 60 strains isolated Azithromycin 500 Mg Tab Greenstone from 1984 to 1989 (P = 0.0047). The susceptibility of M. hominis to clindamycin did not change. We conclude that isolates of M. hominis in the northeastern United States have become more resistant to tetracycline and doxycycline over the past decade.

sobelin 300 mg 2016-12-18

A prospective protocol consisting of clindamycin-gentamicin plus the selective Tab Tambac 200 Mg addition of ampicillin or vancomycin cured 303 of 322 (94%) women with postcesarean endometritis.

sobelin 20 mg 2017-01-07

The aim of the present study was to determine clinical features of Aerococcus infections and the significance of the Aerococcus species isolated from Biaxin 500 Mg Dosage any clinical samples.