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Rozex (Flagyl)
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Rozex

Rozex eliminates bacteria and other microorganisms that cause infections of the reproductive system, gastrointestinal tract, skin, vagina, and other areas of the body. Antibiotics will not work for colds, flu, or other viral infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Other names for this medication:
Acuzole, Amodis, Amrizole, Anazol, Aristogyl, Bemetrazole, Birodogyl, Diazole, Dumozol, Elyzol, Entizol, Etron, Filmet, Flagenase, Flagyl, Flagystatin, Flazol, Gynotran, Klion, Medazol, Metazol, Metrazol, Metris, Metrocream, Metrogel, Metrogyl, Metrolag, Metrolotion, Metronidazol, Metronidazole, Metronide, Metropast, Metrosa, Metrovax, Metrozine, Negazole, Nidagel, Nidazol, Nidazole, Nizole, Noritate, Onida, Orvagil, Protogyl, Rhodogil, Riazole, Rodogyl, Stomorgyl, Supplin, Trichazole, Triconex, Trogyl, Vagilen, Vandazole, Vertisal, Zidoval

Similar Products:
Amoxil, Bactrim, Ampicillin, Augmentin, Macrobid, Trimox, Tinidazole, Biaxin, Chloromycetin, Myambutol

 

Also known as:  Flagyl.

Description

Rozex (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Rozex is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

Rozex 250-mg tablets are round, blue, film coated, with SEARLE and 1831 debossed on one side and Rozex and 250 on the other side; bottles of 50, 100, and 2,500. Rozex 500-mg tablets are oblong, blue, film coated, with Rozex debossed on one side and 500 on the other side; bottles of 50, 100, and 500.

Overdose

Single oral doses of Rozex, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Rozex has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Rozex overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store at room temperature below 25 degrees C (77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Rozex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Hypersensitivity. Rozex Tablets is contraindicated in patients with a prior history of hypersensitivity to metronidazole or other nitroimidazole derivatives. In patients with trichomoniasis, Rozex Tablets is contraindicated during the first trimester of pregnancy.

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To compare the 1-year clinical and microbiological outcomes of an enhanced anti-infective therapy with versus without systemic antimicrobials in patients with generalized aggressive periodontitis (GAP).

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The objective of this study is to compare, in Greece, a region with >20% local resistance to clarithromycin, the efficacy rates of the concomitant versus the sequential H. pylori eradication therapy.

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The current investigation evaluated changes in levels and proportions of 39 bacterial species in subgingival plaque samples after scaling and root planing (SRP) alone or in combination with systemic metronidazole and/or professional cleaning in subjects with chronic periodontitis.

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The Cochrane Pregnancy and Childbirth Group trials register was searched (March 2002).

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A seven-day course of cephazolin and metronidazole chemoprophylaxis for clean-contaminated head and neck oncological procedures is compared to results with previously published antibiotic regimens. Aetiological factors associated with increased rates of wound complications are analyzed. Retrospective analysis of procedures over a six-year period was performed. The overall wound complication rate was 28.1 per cent, comparing favourably with previously published results. A major fistula was the most common complication with a rate of 9.2 per cent. Factors statistically associated with increased rates of wound complications included: radical neck dissection, extended surgical procedures requiring flap reconstruction, previous tracheotomy, and race. This is the largest single institutional study to show that a seven-day course of cephazolin and metronidazole is an effective chemoprophylactic regimen in head and neck surgery.

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Cold-provoked intensification of oxygen consumption was correlated with individual radioresistance of mice. There was a positive correlation between the parameters in normoxia and hyperoxia, and a distinct negative correlation in hypoxia. Radiosensitizer of hypoxic cells, metronidasol, severed the correlation no matter what level of oxygenation in the course of irradiation. The hypothesis for intracellular pO2 as a mediator of the dependence of individual radioresistance on the gas exchange reactivity has been put forward.

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In our retrospective case review, eight cases of metronidazole-resistant trichomoniasis were treated with 1% zinc sulfate douche with or without tinidazole between 2005 and 2012. Except for one patient who was pregnant, seven patients were successfully treated and were negative for microscopic findings with no clinical symptoms at follow up.

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The "new" triple therapy with omeprazole, metronidazole and clarithromycin (administered in a twice-a-day basis and only for one week) had an excellent efficacy for the eradication of H. pylori, significantly higher than that obtained with amoxycillin instead of clarithromycin. Both therapies achieved a high ulcer healing rate when H. pylori was eradicated, even with omeprazole administered only for one week.

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If intestinal spirochetosis is diagnosed to be the sole intestinal pathology in symptomatic patients, the bacteria should be eradicated with metronidazole and a colonoscopy/biopsy follow-up performed, where indicated, in patients with persisting symptoms. Significant results regarding symptoms and treatment of intestinal spirochetosis can be achieved only in a prospective, placebo-controlled, randomized, crossover study. In view of the low prevalence of this condition, such a study is difficult to implement.

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rozex gel 30g 2015-07-18

Hydrophilic matrix tablets based on the alginate system have been used in relation to their possible function in modified drug delivery formulations using metronidazole as a model drug. The matrix tablets were prepared by direct compression using different grades of alginate. The effect of some factors (i.e. particle size of drug, additive used, and pH of medium) on drug release from alginate-based matrix tablets was also investigated. Swelling, erosion, and in vitro release studies of the matrix tablets were carried out in 0.1N HCl or phosphate buffer (pH 6.8). The alginate-based matrix tablets swelled or eroded while in contact with the aqueous medium and formed a continuous gel layer or underwent combination of swelling and erosion. The swelling action of alginate matrices is controlled by the rate of its hydration in the medium. Different grades of alginate insignificantly influenced the Azifast Gel Online matrix swelling in acidic medium but significantly influenced in neutral medium. The presence of ammonium or calcium salts induced tablet disintegration in acidic medium. However, incorporation of calcium acetate and sodium bicarbonate can alter the tablet swelling in acidic medium. Release studies showed that all investigated factors influence the drug release. The extent of matrix swelling, erosion, and diffusion of drug determined the kinetics as well as mechanism of drug release from alginate-based matrix tablets. Most of the release data in acidic medium showed a good fit into Korsmeyer-Peppas equation but fitted well with zero-order release model, in neutral medium.

rozex cream and alcohol 2016-10-23

A clinical research method of multi-center, randomly double-blind, and dose group parallel comparison was adopted. In the study, 533 patients with bacterial vaginosis were randomly divided into two groups, which included 214 cases in the control group (5.0 g metronidazole gel) and 319 cases in Purbac Antibiotic the trial group (5.0 g sucrose gel ). The patients were treated with different medication according to the group where they were. All the cases in these two groups were treated with drugs vaginally twice in a day, morning and evening separately, for 5 days. The curative effect and safety evaluation were assessed from 7 to 10 days and 21 to 30 days after treatment respectively.

rozex metronidazole gel reviews 2017-12-15

Most cases of PID are mild-to-moderate uncomplicated forms that can be treated as outpatients. Apart from Chlamydia trachomatis and Is Norfloxacin A Sulfa Drug Neisseria gonorrhoeae, other pathogens such as Mycoplasma genitalium and bacterial vaginosis (BV)-associated bacteria are playing a significant role in PID and thus must be reckoned with. Moreover, gonococci have increasingly become resistant to the majority of antibiotics. This has led to a universal recommendation to treat N. gonorrhoeae infections with ceftriaxone. A few recent clinical trials have shown that quinolones and azithromycin (with metronidazole) are the best therapeutic options to treat uncomplicated PID.

rozex cream or gel 2016-11-03

From, June 1999 to April 2001, 13 patients with S. maltophilia bacteremia were compared with 39 control-patients who were on the transplantation unit on the same day as the case-patients' positive blood cultures. Information collected included patient demographics, medical history Tetramin Tropical Flakes Review , history of transplantation, transplantation type, graft versus host disease, neutropenia, antibiotic use, chemotherapy, mucositis, diarrhea, the presence of central venous catheter(s), cultures, and concomitant infections.

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Subantimicrobial doses Zitrocin Antibiotic of doxycycline may improve outcomes in rosacea when combined with topical metronidazole and used as maintenance monotherapy.

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To investigate the preferences and practice patterns of urooncologic surgeons in Turkey on bowel preparation and peri-operative Amobay Cl 12h Suspension management for radical cystectomy.