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Side effect occurrence does not only depend on medication you are taking, but also on your
overall health and other factors.
Risk of tendinitis and tendon rupture is increased. This risk is further increased in older patients
usually over 60 years of age, in patients taking corticosteroids, and in patients with kidney, heart and
lung transplants. Discontinue if pain or inflammation in a tendon occurs.
Anaphylactic reactions and allergic skin reactions, serious, occasionally fatal, may occur after first
Hematologic (including agranulocytosis, thrombocytopenia), and renal toxicities may occur after
Hepatotoxicity: Severe, and sometimes fatal, hepatoxicity has been reported. Discontinue immediately
if signs and symptoms of hepatitis occur.
Central nervous system effects, including convulsions, anxiety, confusion, depression, and insomnia
may occur after the first dose. Use with caution in patients with known or suspected disorders that may
predispose them to seizures or lower the seizure threshold.
Clostridium difficile-associated colitis: evaluate if diarrhea occurs.
Peripheral neuropathy: discontinue if symptoms occur in order to prevent
Prolongation of the QT interval and isolated cases of torsade de pointes have
been reported. Avoid use in patients with known prolongation, those with hypokalemia, and with other
drugs that prolong the QT interval.